The interganglionic interruption of the sympathetic chain between the ganglia T1 and T2 is the preferred method for the treatment of craniofacial hyperhidrosis and sympathicogeneous erythema with erythrophobia. In the 90s, the nerve was usually transected or even coagulated at the level of the second rib. Due to the anatomical variability of stellate ganglion (T1), which in a minority of patients extends over the anterior surface of the second rib, sometimes even reaching the lower edge of the rib, a s.c. Horner's syndrome (hanging eyelid, etc.) was not an uncommon outcome. Nowadays, surgical clips of titanium are almost exclusively used for compressing the nerve in order to block the signal transmission. The clips are preferably applied at the lower edge of the second rib (upper limit of the ganglion Th2); this has also has the advantage that the clips could be removed in case of complications or unexpected adverse reactions.